Method for producing pyridylpiperidone compound

ピリジルピペリドン化合物の製造法

Abstract

【課題】医薬中間体として有用なピリジルピペリドン化合物を製造する方法を提供すること。 【解決手段】式(A) (式中、RはC1−C4アルキル基を表す。) で示される化合物と塩基とを反応させ(第1工程)、次いで酸性条件下で加水分解反応させる(第2工程)ことを特徴とする、式(B) で示されるピリジルピペリドン化合物の製造法、及び中間体化合物としての式(C) (式中、RはC1−C4アルキル基を表す。) で示される化合物又はその塩。 【選択図】 なし
PROBLEM TO BE SOLVED: To provide a method for producing a pyridylpiperidone compound useful as an intermediate for a medicine. SOLUTION: This method for producing the pyridylpiperidone compound represented by formula (B) comprises reacting a compound represented by formula (A) (wherein, R is a 1-4C alkyl group) with a base (a first step), and hydrolyzing the product under an acidic condition (a second step). The compound represented by formula (C) (wherein, R is a 1-4C alkyl group) or a salt thereof as the intermediate compound is also provided. COPYRIGHT: (C)2005,JPO&NCIPI

Claims

Description

Topics

Download Full PDF Version (Non-Commercial Use)

Patent Citations (0)

    Publication numberPublication dateAssigneeTitle

NO-Patent Citations (0)

    Title

Cited By (0)

    Publication numberPublication dateAssigneeTitle